李焱简介
【个人简介】
李焱，女，工学博士，教授，硕士生导师，主要从事药物控释靶向给药载体材料研究；纳米材料的生物学效应研究；天然药物的提取分离纯化及活性研究。相关研究工作已获多项基金项目支持，近年来以第一作者或通讯作者已发表学术论文40余篇。
邮箱：yanli@gzu.edu.cn
【主持项目】
1. 省科技厅基础研究重点项目，不同形貌靶向介孔硅基抗肿瘤纳米载药体系的构建及形貌效应研究，项目起止时间：2025.1-2028.12；
2. 省科技厅基础研究重点项目，双药协同治疗乳腺癌纳米靶向载药体系的设计与构建，项目起止时间：2023.1-2026.12；
3. 省教育厅重点领域项目，猕猴桃病害防治新药的开发及作用机制研究，项目起止时间：2021.1-2023.12，
4. 省科技厅基础研究一般项目，兼具主动靶向和环境响应性的抗肿瘤药物载体材料制备及性能研究，项目起止时间：2020.3-2023.3
5. 省科技厅基础研究一般项目，介孔氧化硅纳米材料的制备及其处理含铬废水的效果研究，项目起止时间：2017.12-2020.12
【学术论文】
1. Yuanchan Yu, Fangxiang Song, Maofa Yang*, Shuang Tian, Xiangyu Ji, Xiaofei Yu, Jianfeng Liu, Feng Zhu, Yan Li*. Dual-stimuli-responsive silica-based emamectin benzoate nanodelivery system for effective control of Spodoptera frugiperda and safety assessment toward Microplitis manilae. Chemical Engineering Journal, 2024(497) 154998.
2. Yibing Yan; Fangxiang Song; Songye Li; Tingxian Li; Qian Li; Yan Li* ; Degradablemesoporous organosilicon nanoparticles coated with chitosan-Cu2+ complexes with dual stimulusresponse for efficient prochloraz delivery. International ]ournal of Biological Macromolecules, 2025, 303.
3. Xumin Wu; Bowen Zhang; Keyi Chen; Jiahui Zhao; Yunxing Li; Yan Li*; Xuetao Pei; Yanhua Li；Baffled-flow culture system enables the mass production of megakaryocytes from human embryonic stem cells by enhancing mitochondrial function. Cell Proliferation, 2023, 56(12).
4. Guang-Long Zhang, Zhen-Chao Wang, Cheng-Peng Li, Dan-Ping Chen, Zhu-Rui Li, Yan Li* and Gui-Ping Ouyanga*. Discovery of tryptanthrin analogues bearing F and piperazine moieties as novel phytopathogenic antibacterial and antiviral agents. Pest Management Science, 2024(3):80.
5. Wei Yang, Fangxiang Song, Shuai Wang, Li Zhang, Xian Zeng, Yan Li*. Multifunctional mesoporous silica nanoparticles with different morphological characteristics for in vitro cancer treatment. Colloids and Surfaces A-Physicochemical and Engineering Aspects, 610（2021）, 125717
6. Li Y, Wang S, Song F, et al. A pH-sensitive drug delivery system based on folic acid-targeted HBP-modified mesoporous silica nanoparticles for cancer therapy. Colloids and Surfaces A-Physicochemical and Engineering Aspects, 2020,590.
7. Xian Zeng, Wei Yang, Fang Xiang Song, Hong Xia Wang, Yan Li*. Preparation of functionalized redox response type TiO2&mSiO2 nanomaterials and research on anti-tumor performance. Journal of Drug Delivery Science and Technology,68(2022),103120.
8. Nian Wu; Xian Zeng; Bing Liu; Fang Xiang Song; Meng Lan Chen; Xiao Qin Cai; Hong Huan Luo; Yan Li*; Organic mesoporous silica with variable structures for pH-Stimulated antitumor drug delivery, Journal of Drug Delivery Science and Technology. 2022, 80: 104102.
9. Song F#, Li Y#, Wang S, et al. Multifunctional dual-mesoporous silica nanoparticles loaded with a protein and dual antitumor drugs as a targeted delivery system. New Journal of Chemistry, 2019, 43(44): 17284–17297.
10. Li Zhang, Fangxiang Song, Qianlin Chen, Yan Li*. A Novel Amino and Carboxyl Functionalized Mesoporous Silica as an Efficient Adsorbent for Nickel(II). Journal of Chemical & Engineering Data, 2019, 64(1): 176-188.
