何述钟简介

【个人简介】

 何述钟，博士，教授，贵州大学药学院副院长。主要从事黔产特色天然产物的全合成研究和基于天然产物特色结构的新型合成方法研究。在贵州侗药中活性生物碱的合成、黔产金丝桃花中活性PPAP的合成、箭根薯等药用植物中活性萜类成分的合成领域取得多项研究成果。截至2024年，已主持国家自然科学基金项目4项；以第一作者或通讯作者在Org. Lett., Org. Chem. Front.等期刊发表论文20余篇。

 邮箱：szhe@gzu.edu.cn

【主持项目】

1.  国家自然科学基金地区项目“基于四取代硼酸盐缩环重排反应的palhinine A全合成”

2.  国家自然科学基金地区项目“烷氧基联烯(4+3)反应的研究及其在polygalolides全合成中的应用”

3.  国家自然科学基金地区项目“环氧型taccalonolides的全合成研究”

4.  国家自然科学基金地区项目“真菌杂萜anditomin的对映选择性全合成研究”

【学术论文】

1. Ai Long, Di Li, Bo Yan, Yue Yuan, Haoqi Liu, Lan Yang, Yang Chen*, Shuzhong He* General one-step access to unsymmetric propargylic acetals via alcohol functionalization with allenyl ethers RSC Adv.2025, 15, 11770–11773.

2. Tao Long; Shuzhong He*; Chao Li* Research progress on the radical-polar crossover reaction in total synthesis of natural products. Chin. J. Org. Chem.2025, 45, 748–763.

3. Yanyan Que, Wenli Lei, Yin Fang, Shuzhong He*, Yang Chen* Recent advances in (4 + 3) cycloaddition of allenes. Green Synth. Catal., 2024, 5(4), 270–276.

4. Wenli Lei, Yuyang Song, Ai Long, Yanyan Que, Shuzhong He*; Hang Zhong*; Yang Chen* Stereoselective (4 + 3) cycloadditions of allenyl ethers-furans by chiral auxiliaries inducing and evaluation of anti-breast cancer activity. Front. Plant Sci.2022,12, 1087899–1087909.

5. Gang Yang, Xiangyu Feng, Congcong Han, Yang Chen, Shuzhong He* Synthesis of the ABC Ring System of Wallichanol Natural Product. Chin. J. Org. Chem.2021, 41, 726–730.

6. Xuefeng Liang, Weijian Ye, Waygen Thor, Lantian Sun, Bo Wang, Shuzhong He*, Yuen-Kit Cheng*, Chi-Sing Lee*, Construction of cyclopenta[b]pyran-2-ones viachemoselective (3 + 2) cycloaddition between 2-pyrones and vinyl cyclopropanes. Org. Chem. Front., 2020,7, 840–845.

7. Xian Huang, Waygen Thor, Xiangyu Feng, Liangliang Kang, Min Yang, Chi-Sing Lee*, Yuen-Kit Cheng*, Shuzhong He* (4 + 3) Cycloadditions of Allenyl Ether-Derived Oxygen-Stabilized Oxyallyls with Furans. Org. Chem. Front., 2020,7, 255–260.

8. Congcong Han, Yang Chen, Yin-Cheung Ching, Chi-Sing Lee, Shuzhong He* An approach towards the construction of the tetracyclic skeleton of palhinine alkaloids. Org. Chem. Front., 2020,7, 2243–2246.

9. Shuzhong He,Wei Yang, Lizhi Zhu, Guangyan Du, Chi-Sing Lee* Bioinspired total synthesis of (±)-yezo’otogirin C, Org. Lett.2014, 16(2), 496–499.

10. Shuzhong He, Richard P. Hsung,* William R. Presser, Zhi-Xiong Ma, and Bryan J. HaugenAn approach to cyclohepta[b]indoles through an allenamide (4 + 3) cycloaddition–Grignard cyclization–Chugaev elimination sequence, Org. Lett. 2014, 16, 2180–2183.

【授权专利】

1. 一种非对称炔基缩醛的合成方法CN2024108532575

2. 一种真菌次级代谢产物Ethericin B的合成方法 CN2024108532541

3. 一种天然产物Hypermonones G的合成方法CN2023115611882