王贞超简介
【个人简介】
王贞超，女，理学博士，教授，博士生导师，主要从事化学生物学、药学、农药学等，开展具有医用农用活性的中草药源杂环先导化合物联合创制研究。相关研究工作已获多项基金项目支持，近年来以第一作者或通讯作者已发表学术论文61篇，授权专利8件。
邮箱：zcwang@gzu.edu.cn
【主持项目】
1. 贵州省“第八批高层次创新型百层次人才”项目
2. 国家自然科学基金委地区基金
3. “十四五”国家重点研发计划“子课题
4. 贵州省企事业科协创新示范引领项目
5. 贵州省“科技拔尖人才”项目
6. 绿色农药与农业生物工程教育部重点实验室开放项目
7. 贵州省科技厅基础研究重点项目
8. 国家自然科学基金委青年基金
9. 国家自然科学基金委地区基金
10. 贵州省科技厅基础研究一般项目
11. 贵州省“千层次创新人才”项目
12. 贵州医科大学药用植物功效利用国家重点实验室开放基金项目
13. 贵州省教育厅“青年科技人才成长”项目
14. 贵州省科技厅基础研究一般项目
15. 贵州大学博士基金项目
【学术论文】
1. Le, Y.#; Gan, Y. Y.#; Fu, Y. H.; Liu, J. M.; Li, W.; Xue, Z.; Zhou, Z. X.; Wang, Z. C.*; Ouyang G. P.; Yan, L. J.* Design, synthesis and in vivo biological evaluation of quinazolinone derivatives as EGFR inhibitors for antitumor treatment [J] Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35(1): 555−564.
2. Zhou, X.*; Liu, J. M.; Meng, J.; Fu, Y. H.; Wu, Z. B.; Ouyang, G. P.; Wang, Z. C.* Discovery of facile amides-functionalized rhodanine-3-acetic acid derivatives as potential anticancer agents by disrupting microtubule dynamics [J] Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36, 1996−2009.
3. Bai, N.#; Wang, X. C.#; Wang, Z. C.*; Liu, P. F.; Rong, Z. Q.* Redox-neutral remote amidation of alkenyl alcohols via long-range isomerization/transformation [J] Organic Chemistry Frontiers, 2022, 9: 5942–5948.
4. Zhu, M.; Li, Y.; Chen, D. P.; Li, C. P.; Ouyang, G. P.*; Wang, Z. C.* Allicin-inspired disulfide derivatives containing quinazolin-4(3H)-one as a bacteriostat against Xanthomonas oryzae pv. oryzae [J] Pest Management Science. 2023, 79: 537−547.
5. Zhang, W.; Guo S. X.; Wang, Y.; Tu, H.; Yu, L. J.; Zhao Z. C.; Wang Z. C.*; Wu, J.* Novel trifluoromethylpyridinepiperazine derivatives as potential plant activators [J] Frontiers in Plant Science. 2022, DOI 10.3389/FPLS.2022.1086057.
6. Zhang, G. L.#; Tang, Z. H.#; Fan, S. L.; Li, C. P.; Li, Y.; Liu, W. Q.; Long, X. S.; Zhang, W. J.; Zhang, Y.; Li, Z. R.; Wang, Z. C.*; Chen, D. P.*; Ouyang, G. P.* Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells [J] Journal of Enzyme Inhibition and Medicinal Chemistry, 2023, 38(1): 2163393.
7. Zhang, G. L.; Li, C. P.; Li, Y.; Chen, D. P.; Li, Z. R.; Ouyang, G. P.*; Wang, Z. C.* Discovery and mechanism of azatryptanthrin derivatives as novel anti-Phytopathogenic bacterial agents for potent bactericide candidates [J] Journal of Agricultural and food chemistry, 2023, 71: 6288−6300.
8. Zhang, G. L.#; Li, C. P.#; Li, Y.; Chen, D. P.; Li, Z. R.; Wang, Z. C.* Ouyang, G. P.* Design, synthesis, and mechanism of novel 9‑aliphatic amine tryptanthrin derivatives against phytopathogenic bacteria [J] Journal of Agricultural and food chemistry, 2023, 71: 14232−14242.
9. Zhou, X. H.; Li, C. P.; Wang, W. X.; Zhang, F.; Zhou, Y.; Chen, D. P.*; Wang, Z. C.* DNAzyme mediated catalytic hairpin self-assembly strategy enables the sensitive and facile investigation of N6-methyladenine [J] Sensors and Actuators: B. Chemical, 2023, 397: 134665.
10. Wang, W. H.#; Li, Z. R.#; Zhu, D. X.; Chen, J. Y.; Zhou, Y.; Li, C. P.; Shao, L. H.; Qiu, X. M.; Zhu, M.; Long, H. T.; Chen, D. P.; Ouyang, G. P.; Rong, Z. Q.*; Wang, Z. C.* Design, synthesis, antibacterial evaluation of isopropylamine linked with different substituted phenol and piperazine novel derivatives [J] Pest Manag. Sci., 2024, DOI 10.1002/ps.7986.
【授权专利】
1. 一类含哌嗪类结构衍生物及其应用.
