陈洋博士个人简介

【教师简介】
陈洋,男,理学博士,贵州大学副教授,硕士研究生导师,主要从事具有重要生理活性天然产物的分子构建、结构改造、药理活性及作用机制研究,以及药物开发的应用基础研究。相关研究工作已获多项基金项目支持,近年来以第一作者或通讯作者已发表学术论文20余篇,授权专利2件。
邮箱:ychen1@gzu.edu.cn
【主持项目】
1.国家自然科学基金面上,靶向核糖体抗耐药细菌活性天然产物preuisolactone A构效关系及作用机制研究,82473814,2025.01 - 2028.12,在研,主持;
2.国家重点研发计划子课题,不对称合成手性烯效唑和手性烯唑醇清洁生产工艺研发,2018YFD0200106,2018.07 - 2021.06,结题,主持;
3.国家重点研发计划子课题,诱导马铃薯抗病性的植物免疫诱抗剂鉴选及防治应用,2018YFD020080204,2018.07 - 2021.06,结题,主要参与;
4.国家重点研发计划子课题,南方山地玉米草害发生规律及化学农药减量技术研究,2018YFD0200702,2018.07 - 2021.06,结题,主要参与;
5.贵州省自然科学基金面上项目,骆驼蓬生物碱pegaharines A-F的全合成、衍生化及抗植物病原细菌活性研究,黔科合基础-ZK[2023]一般097,2023.1.1 - 2025.12.31,在研,主持;
6.贵州省科技厅,自然科学基金面上项目,(+)-haedoxan A 的不对称全合成及其杀虫活性研究,黔科合基础[2020]1Y108,2020.01 - 2022.12,结题,主持。
【近三年发表论文】
1. Zuo, M., Chen, Y.*, Zhao, H. Y., Wu, T., He, S. Z., Huang, J.* Synthesis, X-ray, DFT and antibacterial activity of a novel 1-indanone derivative, J. Mol. Struct.,2025, accept. (SCI二区, 2024IF: 4.0)
2. Liu, Q.; Zuo, M.; Song, Y.; He, S.; Huang, J.;Chen, Y.*. Bioinspired Total Synthesis and Biological Activity of Pegaharine A. Pest Manag. Sci., 2024,80 (3), 1372-1381. (SCI一区,2024IF: 3.8)
3. Que, Y.; Lei, W.; Fang, Y.; He, S.; Chen, Y.*, Recent Advances in (4 + 3) Cycloaddition of Allenes. Green Synth. Catal.2024. DOI: 10.1016/j.gresc.2023.11.010(SCI一区,2024 IF: 8.2)
4. Li, M.; Chen, P.; Liu, H.; Huang, J.*; Chen, Y.*. Review of the Total Synthesis of the Aromatic Abietane Diterpenoid Ferruginol. Synthesis-Stuttgart 2024, 56(09), 1355-1368. (IF = 2.4)(SCI二区,2024IF = 2.2)
5. Ai, L.; Fu, S.; Li, Y.; Zuo, M.; Huang, W.; Huang, J.; Jin, Z.; Chen, Y.*, Natural products-based: Synthesis and antifungal activity evaluation of novel L-pyroglutamic acid analogues. Front. Plant Sci. 2022,13, 1102411. (SCI一区,2022 IF = 6.6)
6. Lei, W.; Song, Y.; Long, A.; Que, Y.; He, S.*; Zhong, H.*; Chen, Y.*, Stereoselective (4 + 3) cycloadditions of allenyl ethers-furans by chiral auxiliaries inducing and evaluation of anti-breast cancer activity. Front. Plant Sci. 2022,13, 1087899. (SCI一区,2022 IF = 6.6)
7. Zhao, H.; Pan, H.; Yao, Y.; Huang, J.*; Chen, Y.*, Recent Advances in the Total Synthesis of Cephalotane-Type Norditerpenoids from Cephalotaxus sinensis. Synthesis-Stuttgart 2022,54 (15), 3317-3327.(SCI二区,IF = 3.0)
【授权专利】
1. Chen, Y.*; Pan, H.; Zhao, H. Preparation of sex attractant for Phthorimaea operculella. CN115490589, 2024.
2. Chen, Y.*; Ai, L.; Li, M.; Pan, H. Method for preparing 4-chloroindole-3-acetic acid using trifluoroacetic acid. CN114573496, 2024.